Elevated lipase after Maropitant (Cerenia) in dogs

168 reports to the FDA describe elevated lipase in dogs given Maropitant. That is 1.4% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

168Reports

72%Marked serious

6.5%Recovered

51%Died or euthanised

3 daysTypical onset

How soon it started

Same day

35 26%

1–2 days

32 24%

3–7 days

11 8.1%

1–4 weeks

22 16%

Over a month

35 26%

How the animals did

Recovered

10 6.0%

Recovered with lasting effects

1 0.6%

Still unwell when reported

54 32%

Died

36 21%

Euthanised

50 30%

Not known

17 10%

Problems reported at the same time

112 67%

101 60%

92 55%

87 52%

84 50%

83 49%

71 42%

61 36%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause elevated lipase in dogs?: 168 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated lipase with similar medicines

Elevated lipase after Capromorelin (Entyce) 20 reports · 1.3% of its reports

All reported side effects of Maropitant in dogs · Medicines most reported with elevated lipase