Elevated amylase after Maropitant (Cerenia) in dogs

The FDA has received 214 reports of elevated amylase in dogs after Maropitant. That is 1.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

214Reports

78%Marked serious

3.7%Recovered

53%Died or euthanised

4 daysTypical onset

How soon it started

Same day

40 23%

1–2 days

35 20%

3–7 days

24 14%

1–4 weeks

29 16%

Over a month

49 28%

How the animals did

Recovered

8 3.7%

Still unwell when reported

72 34%

Died

46 21%

Euthanised

68 32%

Not known

20 9.3%

Problems reported at the same time

139 65%

136 64%

134 63%

117 55%

114 53%

104 49%

72 34%

71 33%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Maropitant prevents vomiting and motion sickness.

Products with this ingredient include Cerenia. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Maropitant cause elevated amylase in dogs?: 214 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Maropitant in dogs · Medicines most reported with elevated amylase