Respiratory distress after Lokivetmab (Cytopoint) in dogs

The FDA has received 22 reports of respiratory distress in dogs after Lokivetmab. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

22Reports

100%Marked serious

9.1%Recovered

50%Died or euthanised

Same dayTypical onset

How soon it started

Same day

10 56%

1–2 days

4 22%

3–7 days

1 5.6%

1–4 weeks

0 0.0%

Over a month

3 17%

How the animals did

Recovered

2 9.1%

Still unwell when reported

9 41%

Died

5 23%

Euthanised

6 27%

Problems reported at the same time

11 50%

10 45%

9 41%

6 27%

6 27%

Abnormal radiograph finding

6 27%

Swelling

6 27%

Fever

4 18%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause respiratory distress in dogs?: 22 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Respiratory distress with similar medicines

Respiratory distress after Bedinvetmab (Librela) 53 reports · 0.3% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with respiratory distress