Corneal ulcer after Lokivetmab (Cytopoint) in dogs

43 reports to the FDA describe corneal ulcer in dogs given Lokivetmab. That is 0.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports

65%Marked serious

16%Recovered

4.7%Died or euthanised

1 daysTypical onset

How soon it started

Same day

13 37%

1–2 days

7 20%

3–7 days

0 0.0%

1–4 weeks

9 26%

Over a month

6 17%

How the animals did

Recovered

7 16%

Still unwell when reported

26 60%

Euthanised

2 4.7%

Not known

8 19%

Problems reported at the same time

Didn't work as expected

13 30%

Ocular discharge

13 30%

Vomiting

11 26%

Squinting

11 26%

Neurogenic keratoconjunctivitis sicca (kcs)

10 23%

Eye disorder (for photophobia see 'neurological')

9 21%

Swelling

8 19%

Loss of appetite

8 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Lokivetmab controls allergic itch for 4–8 weeks per injection.

Products with this ingredient include Cytopoint. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Lokivetmab cause corneal ulcer in dogs?: 43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Corneal ulcer with similar medicines

Corneal ulcer after Bedinvetmab (Librela) 32 reports · 0.2% of its reports

All reported side effects of Lokivetmab in dogs · Medicines most reported with corneal ulcer