Vestibular disorder after Ketoconazole in dogs

30 reports to the FDA describe vestibular disorder in dogs given Ketoconazole. That is 1.3% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

30Reports

73%Marked serious

23%Recovered

3.3%Died or euthanised

Same dayTypical onset

How soon it started

Same day

15 56%

1–2 days

3 11%

3–7 days

1 3.7%

1–4 weeks

4 15%

Over a month

4 15%

How the animals did

Recovered

7 23%

Still unwell when reported

13 43%

Died

1 3.3%

Not known

9 30%

Problems reported at the same time

Loss of appetite

15 50%

Nystagmus

12 40%

Wobbliness (ataxia)

11 37%

Head tilt - ear disorder

11 37%

11 37%

8 27%

7 23%

6 20%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Ketoconazole cause vestibular disorder in dogs?: 30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vestibular disorder with similar medicines

Vestibular disorder after Polysulfated Glycosaminoglycan 21 reports · 0.4% of its reports
Vestibular disorder after Florfenicol + Mometasone + Terbinafine 220 reports · 6.2% of its reports
Vestibular disorder after Betamethasone + Florfenicol + Terbinafine 22 reports · 0.9% of its reports
Vestibular disorder after Meclizine 42 reports · 39% of its reports

All reported side effects of Ketoconazole in dogs · Medicines most reported with vestibular disorder