Vestibular disorder after Meclizine in dogs

The FDA has received 42 reports of vestibular disorder in dogs after Meclizine. That is 39% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

42Reports

83%Marked serious

4.8%Recovered

24%Died or euthanised

11 daysTypical onset

How soon it started

Same day

6 17%

1–2 days

2 5.6%

3–7 days

6 17%

1–4 weeks

12 33%

Over a month

10 28%

How the animals did

Recovered

2 4.8%

Still unwell when reported

21 50%

Died

3 7.1%

Euthanised

7 17%

Not known

9 21%

Problems reported at the same time

Wobbliness (ataxia)

20 48%

Nystagmus

19 45%

Head tilt - neurological disorder

18 43%

17 40%

16 38%

16 38%

12 29%

10 24%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Meclizine cause vestibular disorder in dogs?: 42 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vestibular disorder with similar medicines

Vestibular disorder after Polysulfated Glycosaminoglycan 21 reports · 0.4% of its reports
Vestibular disorder after Florfenicol + Mometasone + Terbinafine 220 reports · 6.2% of its reports
Vestibular disorder after Betamethasone + Florfenicol + Terbinafine 22 reports · 0.9% of its reports
Vestibular disorder after Ketoconazole 30 reports · 1.3% of its reports

All reported side effects of Meclizine in dogs · Medicines most reported with vestibular disorder