Lameness after Ivermectin (Heartgard) in dogs
59 reports to the FDA describe lameness in dogs given Ivermectin. That is 0.5% of all reports for this medicine, compared with 0.6% across reports for all dog medicines.
59Reports
36%Marked serious
25%Recovered
6.8%Died or euthanised
74 daysTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Ivermectin prevents heartworm disease (monthly).
Products with this ingredient include Heartgard. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Ivermectin cause lameness in dogs?
- 59 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 74 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Lameness with similar medicines
- Lameness after Ivermectin + Pyrantel (Heartgard Plus) 319 reports · 0.2% of its reports
- Lameness after Milbemycin Oxime + Spinosad (Trifexis) 452 reports · 0.3% of its reports
- Lameness after Moxidectin (ProHeart 6) 363 reports · 0.7% of its reports
- Lameness after Milbemycin Oxime + Praziquantel (Interceptor Plus) 233 reports · 0.7% of its reports
- Lameness after Milbemycin Oxime (Interceptor) 115 reports · 0.4% of its reports
- Lameness after Selamectin (Revolution) 100 reports · 0.3% of its reports
All reported side effects of Ivermectin in dogs · Medicines most reported with lameness