Weight gain after Ivermectin + Praziquantel + Pyrantel (Iverhart Max) in dogs

23 reports to the FDA describe weight gain in dogs given Ivermectin + Praziquantel + Pyrantel. That is 0.3% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported less often than average with this medicine.

23Reports
30%Marked serious
8.7%Recovered
0.0%Died or euthanised
–Typical onset
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How the animals did

Recovered
2 8.7%
Still unwell when reported
6 26%
Not known
15 65%

Problems reported at the same time

1 4.3%
Unpalatable
1 4.3%
1 4.3%

Age of the animals

Under 1 year
0
1–3 years
8
4–7 years
10
8–11 years
4
12+ years
0

About this medicine

Ivermectin prevents heartworm disease (monthly). Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Iverhart Max. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Ivermectin + Praziquantel + Pyrantel cause weight gain in dogs?
23 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weight gain with similar medicines

All reported side effects of Ivermectin + Praziquantel + Pyrantel in dogs · Medicines most reported with weight gain