Sedation after Isoflurane in dogs

The FDA has received 56 reports of sedation in dogs after Isoflurane. That is 2.0% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

56Reports
36%Marked serious
61%Recovered
5.4%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
43 83%
1–2 days
5 9.6%
3–7 days
1 1.9%
1–4 weeks
1 1.9%
Over a month
2 3.8%

How the animals did

Recovered
32 57%
Recovered with lasting effects
2 3.6%
Still unwell when reported
8 14%
Died
2 3.6%
Euthanised
1 1.8%
Not known
11 20%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
14
4–7 years
11
8–11 years
14
12+ years
3

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause sedation in dogs?
56 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Sedation with similar medicines

All reported side effects of Isoflurane in dogs · Medicines most reported with sedation