Decreased heart rate after Isoflurane in dogs

46 reports to the FDA describe decreased heart rate in dogs given Isoflurane. That is 1.7% of all reports for this medicine, compared with 0.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

46Reports

78%Marked serious

59%Recovered

30%Died or euthanised

Same dayTypical onset

How soon it started

Same day

38 97%

1–2 days

1 2.6%

3–7 days

0 0.0%

1–4 weeks

0 0.0%

Over a month

0 0.0%

How the animals did

Recovered

27 59%

Still unwell when reported

3 6.5%

Died

13 28%

Euthanised

1 2.2%

Not known

2 4.3%

Problems reported at the same time

13 28%

11 24%

5 11%

4 8.7%

Didn't work as expected

4 8.7%

Pale mucous membrane

4 8.7%

Decreased respiratory rate

4 8.7%

Low blood pressure

4 8.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Isoflurane cause decreased heart rate in dogs?: 46 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased heart rate with similar medicines

Decreased heart rate after Butorphanol 47 reports · 1.1% of its reports
Decreased heart rate after Propofol 35 reports · 1.1% of its reports
Decreased heart rate after Atipamezole 27 reports · 1.0% of its reports
Decreased heart rate after Ketamine 20 reports · 1.1% of its reports

All reported side effects of Isoflurane in dogs · Medicines most reported with decreased heart rate