Proteinuria after Insulin in dogs

The FDA has received 66 reports of proteinuria in dogs after Insulin. That is 0.9% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

66Reports

80%Marked serious

15%Recovered

20%Died or euthanised

36 daysTypical onset

How soon it started

Same day

4 18%

1–2 days

2 9.1%

3–7 days

0 0.0%

1–4 weeks

4 18%

Over a month

12 55%

How the animals did

Recovered

1 1.5%

Recovered with lasting effects

9 14%

Still unwell when reported

22 33%

Died

4 6.1%

Euthanised

9 14%

Not known

21 32%

Problems reported at the same time

Liver problems

34 52%

Didn't work as expected

29 44%

25 38%

25 38%

24 36%

23 35%

22 33%

19 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause proteinuria in dogs?: 66 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 36 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

Proteinuria after Trilostane (Vetoryl) 556 reports · 4.7% of its reports
Proteinuria after Phenylpropanolamine (Proin) 50 reports · 1.2% of its reports
Proteinuria after Levothyroxine 48 reports · 1.6% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with proteinuria