Hypochloraemia after Insulin in dogs

The FDA has received 79 reports of hypochloraemia in dogs after Insulin. That is 1.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

79Reports

82%Marked serious

16%Recovered

22%Died or euthanised

128 daysTypical onset

How soon it started

Same day

3 6.7%

1–2 days

0 0.0%

3–7 days

3 6.7%

1–4 weeks

6 13%

Over a month

33 73%

How the animals did

Recovered

1 1.3%

Recovered with lasting effects

12 15%

Still unwell when reported

27 34%

Died

7 8.9%

Euthanised

10 13%

Not known

22 28%

Problems reported at the same time

51 65%

50 63%

38 48%

36 46%

Didn't work as expected

31 39%

Kidney problems

28 35%

Elevated cholesterol (total)

27 34%

Loss of appetite

27 34%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause hypochloraemia in dogs?: 79 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 128 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypochloraemia with similar medicines

Hypochloraemia after Trilostane (Vetoryl) 328 reports · 2.8% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with hypochloraemia