Excessive urination after Insulin in dogs

The FDA has received 473 reports of excessive urination in dogs after Insulin. That is 6.4% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

473Reports

34%Marked serious

13%Recovered

7.6%Died or euthanised

40 daysTypical onset

How soon it started

Same day

12 8.1%

1–2 days

13 8.7%

3–7 days

17 11%

1–4 weeks

27 18%

Over a month

80 54%

How the animals did

Recovered

50 11%

Recovered with lasting effects

10 2.1%

Still unwell when reported

86 18%

Died

17 3.6%

Euthanised

19 4.0%

Not known

291 62%

Problems reported at the same time

Excessive thirst

425 90%

Didn't work as expected

344 73%

209 44%

96 20%

71 15%

56 12%

50 11%

40 8.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

256

12+ years

116

About this medicine

Insulin treats diabetes.

Questions owners ask

Can Insulin cause excessive urination in dogs?: 473 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 40 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Excessive urination with similar medicines

Excessive urination after Trilostane (Vetoryl) 772 reports · 6.5% of its reports
Excessive urination after Phenylpropanolamine (Proin) 81 reports · 2.0% of its reports
Excessive urination after Levothyroxine 132 reports · 4.4% of its reports

All reported side effects of Insulin in dogs · Medicines most reported with excessive urination