Retching after Fluralaner (Bravecto) in dogs

The FDA has received 154 reports of retching in dogs after Fluralaner. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

154Reports
68%Marked serious
42%Recovered
11%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
56 51%
1–2 days
24 22%
3–7 days
12 11%
1–4 weeks
4 3.6%
Over a month
14 13%

How the animals did

Recovered
61 40%
Recovered with lasting effects
3 1.9%
Still unwell when reported
56 36%
Died
8 5.2%
Euthanised
9 5.8%
Not known
17 11%

Problems reported at the same time

Age of the animals

Under 1 year
18
1–3 years
51
4–7 years
38
8–11 years
24
12+ years
19

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause retching in dogs?
154 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Retching with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with retching