Decreased drinking after Fluralaner (Bravecto) in dogs

The FDA has received 198 reports of decreased drinking in dogs after Fluralaner. That is 0.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

198Reports
82%Marked serious
17%Recovered
11%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
50 32%
1–2 days
62 40%
3–7 days
21 14%
1–4 weeks
5 3.2%
Over a month
17 11%

How the animals did

Recovered
32 16%
Recovered with lasting effects
1 0.5%
Still unwell when reported
120 61%
Died
9 4.5%
Euthanised
12 6.1%
Not known
24 12%

Problems reported at the same time

Age of the animals

Under 1 year
18
1–3 years
47
4–7 years
60
8–11 years
51
12+ years
19

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause decreased drinking in dogs?
198 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Decreased drinking with similar medicines

All reported side effects of Fluralaner in dogs · Medicines most reported with decreased drinking