Appetite loss after Fluralaner (Bravecto) in dogs

206 reports to the FDA describe appetite loss in dogs given Fluralaner. That is 0.3% of all reports for this medicine, compared with 0.3% across reports for all dog medicines.

206Reports

60%Marked serious

24%Recovered

11%Died or euthanised

1 daysTypical onset

How soon it started

Same day

48 39%

1–2 days

41 34%

3–7 days

10 8.2%

1–4 weeks

10 8.2%

Over a month

13 11%

How the animals did

Recovered

45 22%

Recovered with lasting effects

4 1.9%

Still unwell when reported

110 53%

Died

11 5.3%

Euthanised

12 5.8%

Not known

24 12%

Problems reported at the same time

107 52%

92 45%

70 34%

23 11%

22 11%

21 10%

19 9.2%

17 8.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluralaner kills fleas and ticks for up to 12 weeks (chewable or spot-on).

Products with this ingredient include Bravecto. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

In 2018 the FDA alerted owners and vets that isoxazoline products have been associated with neurologic reactions such as muscle tremors, wobbliness (ataxia) and seizures, including in animals with no history of them.

Questions owners ask

Can Fluralaner cause appetite loss in dogs?: 206 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Appetite loss with similar medicines

Appetite loss after Afoxolaner (NexGard) 601 reports · 1.1% of its reports
Appetite loss after Sarolaner (Simparica) 48 reports · 0.3% of its reports
Appetite loss after Lotilaner (Credelio) 37 reports · 0.4% of its reports
Appetite loss after Afoxolaner + Moxidectin + Pyrantel (NexGard PLUS) 37 reports · 0.4% of its reports
Appetite loss after Lotilaner + Moxidectin + Praziquantel + Pyrantel (Credelio Quattro) 20 reports · 0.6% of its reports

All reported side effects of Fluralaner in dogs · Medicines most reported with appetite loss