Polypnoea after Fluoxetine in dogs

The FDA has received 30 reports of polypnoea in dogs after Fluoxetine. That is 1.2% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

30Reports

0.0%Marked serious

0.0%Recovered

3.3%Died or euthanised

–Typical onset

How the animals did

Died

1 3.3%

Not known

29 97%

Problems reported at the same time

10 33%

8 27%

7 23%

6 20%

6 20%

Eye or vision problems

5 17%

Restlessness or agitation

5 17%

Vomiting

4 13%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause polypnoea in dogs?: 30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Polypnoea with similar medicines

Polypnoea after Selegiline (Anipryl) 214 reports · 5.2% of its reports
Polypnoea after Clomipramine (Clomicalm) 23 reports · 1.5% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with polypnoea