Loose stool after Fluoxetine in dogs

The FDA has received 24 reports of loose stool in dogs after Fluoxetine. That is 0.9% of all reports for this medicine, compared with 0.9% across reports for all dog medicines.

24Reports

38%Marked serious

21%Recovered

0.0%Died or euthanised

13 daysTypical onset

How soon it started

Same day

2 17%

1–2 days

2 17%

3–7 days

1 8.3%

1–4 weeks

2 17%

Over a month

5 42%

How the animals did

Recovered

2 8.3%

Recovered with lasting effects

3 13%

Still unwell when reported

8 33%

Not known

11 46%

Problems reported at the same time

Loss of appetite

12 50%

Lethargy

7 29%

Vomiting

5 21%

Didn't work as expected

4 17%

Behaviour change

3 13%

Apprehension

2 8.3%

Restlessness or agitation

2 8.3%

Drooling

2 8.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Fluoxetine treats anxiety and behaviour problems.

Questions owners ask

Can Fluoxetine cause loose stool in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 13 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loose stool with similar medicines

Loose stool after Gabapentin 158 reports · 1.8% of its reports
Loose stool after Selegiline (Anipryl) 23 reports · 0.6% of its reports
Loose stool after Trazodone 47 reports · 1.9% of its reports

All reported side effects of Fluoxetine in dogs · Medicines most reported with loose stool