Skin redness after Fipronil in dogs

The FDA has received 25 reports of skin redness in dogs after Fipronil. That is 1.8% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Fipronil kills fleas and ticks (spot-on).

Questions owners ask

Can Fipronil cause skin redness in dogs?

25 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 30 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Skin redness with similar medicines

• Skin redness after Spinosad (Comfortis) 266 reports · 0.5% of its reports
• Skin redness after Lufenuron + Milbemycin Oxime (Sentinel) 119 reports · 0.5% of its reports
• Skin redness after Imidacloprid + Moxidectin (Advantage Multi) 470 reports · 3.6% of its reports
• Skin redness after Nitenpyram (Capstar) 102 reports · 0.9% of its reports
• Skin redness after Lufenuron + Milbemycin Oxime + Praziquantel (Sentinel Spectrum) 41 reports · 0.4% of its reports
• Skin redness after Fipronil + S-methoprene (Frontline Plus) 47 reports · 1.6% of its reports
• Skin redness after Flumethrin + Imidacloprid (Seresto) 101 reports · 4.4% of its reports
• Skin redness after Imidacloprid 29 reports · 1.5% of its reports
• Skin redness after Imidacloprid + Permethrin + Pyriproxyfen 33 reports · 4.5% of its reports

All reported side effects of Fipronil in dogs · Medicines most reported with skin redness