Proteinuria after Famotidine in dogs

The FDA has received 78 reports of proteinuria in dogs after Famotidine. That is 3.0% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

78Reports

74%Marked serious

3.8%Recovered

47%Died or euthanised

11 daysTypical onset

How soon it started

Same day

7 12%

1–2 days

6 10%

3–7 days

11 19%

1–4 weeks

19 32%

Over a month

16 27%

How the animals did

Recovered

3 3.8%

Still unwell when reported

24 31%

Died

11 14%

Euthanised

26 33%

Not known

14 18%

Problems reported at the same time

56 72%

55 71%

50 64%

45 58%

43 55%

35 45%

25 32%

23 29%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Famotidine cause proteinuria in dogs?: 78 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 11 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Proteinuria with similar medicines

Proteinuria after Melarsomine (Immiticide) 46 reports · 0.2% of its reports
Proteinuria after Polysulfated Glycosaminoglycan 61 reports · 1.1% of its reports
Proteinuria after Diphenhydramine 52 reports · 1.1% of its reports
Proteinuria after Butorphanol 41 reports · 0.9% of its reports
Proteinuria after Cefpodoxime 74 reports · 1.8% of its reports
Proteinuria after Tramadol 70 reports · 1.9% of its reports
Proteinuria after Florfenicol + Mometasone + Terbinafine 24 reports · 0.7% of its reports
Proteinuria after Desoxycorticosterone Pivalate 40 reports · 1.2% of its reports
Proteinuria after Propofol 20 reports · 0.7% of its reports
Proteinuria after Dirlotapide 20 reports · 0.7% of its reports

All reported side effects of Famotidine in dogs · Medicines most reported with proteinuria