Injection site reaction after Enrofloxacin (Baytril) in dogs

The FDA has received 204 reports of injection site reaction in dogs after Enrofloxacin. That is 5.4% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

204Reports
56%Marked serious
24%Recovered
8.8%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
20 16%
1–2 days
17 13%
3–7 days
30 24%
1–4 weeks
44 35%
Over a month
16 13%

How the animals did

Recovered
46 23%
Recovered with lasting effects
2 1.0%
Still unwell when reported
20 9.8%
Died
8 3.9%
Euthanised
10 4.9%
Not known
118 58%

Problems reported at the same time

Swelling
35 17%
Loss of appetite
18 8.8%
Death
18 8.8%
Hair loss
16 7.8%
Lethargy
16 7.8%
Fever
13 6.4%
Liver problems
11 5.4%
Lameness
9 4.4%

Age of the animals

Under 1 year
27
1–3 years
39
4–7 years
51
8–11 years
33
12+ years
26

About this medicine

Enrofloxacin treats bacterial infections.

Products with this ingredient include Baytril. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Enrofloxacin cause injection site reaction in dogs?
204 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

All reported side effects of Enrofloxacin in dogs · Medicines most reported with injection site reaction