Hypochloraemia after Enrofloxacin (Baytril) in dogs

The FDA has received 40 reports of hypochloraemia in dogs after Enrofloxacin. That is 1.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

40Reports
93%Marked serious
15%Recovered
50%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
5 14%
1–2 days
2 5.7%
3–7 days
11 31%
1–4 weeks
4 11%
Over a month
13 37%

How the animals did

Recovered
5 13%
Recovered with lasting effects
1 2.5%
Still unwell when reported
11 28%
Died
9 23%
Euthanised
11 28%
Not known
3 7.5%

Problems reported at the same time

Liver problems
32 80%
Hyponatremia
32 80%
Loss of appetite
29 73%
Vomiting
27 68%
Lethargy
25 63%
Kidney problems
23 57%
Death
20 50%
Diarrhea
20 50%

Age of the animals

Under 1 year
0
1–3 years
13
4–7 years
9
8–11 years
14
12+ years
4

About this medicine

Enrofloxacin treats bacterial infections.

Products with this ingredient include Baytril. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Enrofloxacin cause hypochloraemia in dogs?
40 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypochloraemia with similar medicines

All reported side effects of Enrofloxacin in dogs · Medicines most reported with hypochloraemia