Ocular discharge after Doxycycline in dogs

The FDA has received 45 reports of ocular discharge in dogs after Doxycycline. That is 1.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

45Reports

73%Marked serious

11%Recovered

16%Died or euthanised

27 daysTypical onset

How soon it started

Same day

7 19%

1–2 days

2 5.6%

3–7 days

2 5.6%

1–4 weeks

10 28%

Over a month

15 42%

How the animals did

Recovered

5 11%

Still unwell when reported

21 47%

Died

2 4.4%

Euthanised

5 11%

Not known

12 27%

Problems reported at the same time

20 44%

16 36%

14 31%

14 31%

13 29%

11 24%

11 24%

10 22%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Doxycycline treats bacterial and tick-borne infections.

Questions owners ask

Can Doxycycline cause ocular discharge in dogs?: 45 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 27 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Ocular discharge with similar medicines

Ocular discharge after Amoxicillin + Clavulanate (Clavamox) 86 reports · 1.6% of its reports
Ocular discharge after Cefovecin (Convenia) 35 reports · 0.9% of its reports
Ocular discharge after Enrofloxacin (Baytril) 50 reports · 1.3% of its reports
Ocular discharge after Metronidazole 28 reports · 0.9% of its reports

All reported side effects of Doxycycline in dogs · Medicines most reported with ocular discharge