Neutropenia after Distemper-parvo Vaccine in dogs

65 reports to the FDA describe neutropenia in dogs given Distemper-parvo Vaccine. That is 1.0% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

65Reports

77%Marked serious

9.2%Recovered

34%Died or euthanised

9 daysTypical onset

How soon it started

Same day

13 24%

1–2 days

5 9.1%

3–7 days

8 15%

1–4 weeks

13 24%

Over a month

16 29%

How the animals did

Recovered

5 7.7%

Recovered with lasting effects

1 1.5%

Still unwell when reported

26 40%

Died

9 14%

Euthanised

13 20%

Not known

11 17%

Problems reported at the same time

33 51%

32 49%

29 45%

23 35%

23 35%

22 34%

22 34%

21 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Distemper-parvo Vaccine cause neutropenia in dogs?: 65 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 9 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutropenia with similar medicines

Neutropenia after Rabies Vaccine 61 reports · 0.6% of its reports
Neutropenia after Bordetella Vaccine 68 reports · 0.7% of its reports
Neutropenia after Leptospirosis Vaccine 66 reports · 0.8% of its reports

All reported side effects of Distemper-parvo Vaccine in dogs · Medicines most reported with neutropenia