Neutropenia after Bordetella Vaccine in dogs

68 reports to the FDA describe neutropenia in dogs given Bordetella Vaccine. That is 0.7% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

68Reports

87%Marked serious

10%Recovered

37%Died or euthanised

12 daysTypical onset

How soon it started

Same day

13 22%

1–2 days

4 6.9%

3–7 days

8 14%

1–4 weeks

14 24%

Over a month

19 33%

How the animals did

Recovered

5 7.4%

Recovered with lasting effects

2 2.9%

Still unwell when reported

25 37%

Died

5 7.4%

Euthanised

20 29%

Not known

11 16%

Problems reported at the same time

37 54%

34 50%

33 49%

28 41%

26 38%

25 37%

24 35%

23 34%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause neutropenia in dogs?: 68 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 12 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutropenia with similar medicines

Neutropenia after Rabies Vaccine 61 reports · 0.6% of its reports
Neutropenia after Leptospirosis Vaccine 66 reports · 0.8% of its reports
Neutropenia after Distemper-parvo Vaccine 65 reports · 1.0% of its reports

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with neutropenia