Leucopenia after Distemper-parvo Vaccine in dogs

72 reports to the FDA describe leucopenia in dogs given Distemper-parvo Vaccine. That is 1.1% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

72Reports

76%Marked serious

6.9%Recovered

32%Died or euthanised

5 daysTypical onset

How soon it started

Same day

13 21%

1–2 days

13 21%

3–7 days

8 13%

1–4 weeks

16 25%

Over a month

13 21%

How the animals did

Recovered

5 6.9%

Still unwell when reported

40 56%

Died

10 14%

Euthanised

13 18%

Not known

4 5.6%

Problems reported at the same time

43 60%

41 57%

35 49%

29 40%

28 39%

26 36%

23 32%

23 32%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Distemper-parvo Vaccine cause leucopenia in dogs?: 72 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucopenia with similar medicines

Leucopenia after Rabies Vaccine 76 reports · 0.8% of its reports
Leucopenia after Bordetella Vaccine 78 reports · 0.8% of its reports
Leucopenia after Leptospirosis Vaccine 64 reports · 0.8% of its reports

All reported side effects of Distemper-parvo Vaccine in dogs · Medicines most reported with leucopenia