Hypoproteinaemia after Deracoxib (Deramaxx) in dogs

The FDA has received 361 reports of hypoproteinaemia in dogs after Deracoxib. That is 3.3% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

361Reports
19%Marked serious
3.0%Recovered
48%Died or euthanised
10 daysTypical onset
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How soon it started

Same day
7 15%
1–2 days
4 8.5%
3–7 days
12 26%
1–4 weeks
8 17%
Over a month
16 34%

How the animals did

Recovered
10 2.8%
Recovered with lasting effects
1 0.3%
Still unwell when reported
20 5.5%
Died
146 40%
Euthanised
26 7.2%
Not known
158 44%

Problems reported at the same time

Age of the animals

Under 1 year
8
1–3 years
57
4–7 years
117
8–11 years
127
12+ years
51

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause hypoproteinaemia in dogs?
361 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 10 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypoproteinaemia with similar medicines

All reported side effects of Deracoxib in dogs · Medicines most reported with hypoproteinaemia