Gastric perforation after Deracoxib (Deramaxx) in dogs

340 reports to the FDA describe gastric perforation in dogs given Deracoxib. That is 3.1% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

340Reports
29%Marked serious
8.8%Recovered
52%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
7 9.7%
1–2 days
7 9.7%
3–7 days
21 29%
1–4 weeks
17 24%
Over a month
20 28%

How the animals did

Recovered
27 7.9%
Recovered with lasting effects
3 0.9%
Still unwell when reported
25 7.4%
Died
154 45%
Euthanised
24 7.1%
Not known
107 31%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
68
4–7 years
123
8–11 years
112
12+ years
24

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause gastric perforation in dogs?
340 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Gastric perforation with similar medicines

All reported side effects of Deracoxib in dogs · Medicines most reported with gastric perforation