Elevated gamma-glutamyl transferase (ggt) after Deracoxib (Deramaxx) in dogs

142 reports to the FDA describe elevated gamma-glutamyl transferase (ggt) in dogs given Deracoxib. That is 1.3% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

142Reports

15%Marked serious

1.4%Recovered

27%Died or euthanised

29 daysTypical onset

How soon it started

Same day

1 6.7%

1–2 days

1 6.7%

3–7 days

1 6.7%

1–4 weeks

5 33%

Over a month

7 47%

How the animals did

Recovered

2 1.4%

Still unwell when reported

12 8.5%

Died

30 21%

Euthanised

9 6.3%

Not known

89 63%

Problems reported at the same time

134 94%

62 44%

61 43%

43 30%

41 29%

39 27%

30 21%

Elevated cholesterol (total)

27 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause elevated gamma-glutamyl transferase (ggt) in dogs?: 142 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 29 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated gamma-glutamyl transferase (ggt) with similar medicines

Elevated gamma-glutamyl transferase (ggt) after Carprofen (Rimadyl) 1,078 reports · 2.3% of its reports
Elevated gamma-glutamyl transferase (ggt) after Grapiprant (Galliprant) 89 reports · 1.0% of its reports
Elevated gamma-glutamyl transferase (ggt) after Meloxicam (Metacam) 85 reports · 1.1% of its reports
Elevated gamma-glutamyl transferase (ggt) after Firocoxib (Previcox) 91 reports · 1.1% of its reports

All reported side effects of Deracoxib in dogs · Medicines most reported with elevated gamma-glutamyl transferase (ggt)