Elevated bile acids after Deracoxib (Deramaxx) in dogs

46 reports to the FDA describe elevated bile acids in dogs given Deracoxib. That is 0.4% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

46Reports

15%Marked serious

4.3%Recovered

15%Died or euthanised

–Typical onset

How the animals did

Recovered with lasting effects

2 4.3%

Still unwell when reported

6 13%

Died

5 11%

Euthanised

2 4.3%

Not known

31 67%

Problems reported at the same time

Liver problems

36 78%

Vomiting

17 37%

Loss of appetite

17 37%

Ultrasound, liver abnormal

13 28%

12 26%

11 24%

8 17%

8 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Deracoxib relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Deramaxx. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Deracoxib cause elevated bile acids in dogs?: 46 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Elevated bile acids with similar medicines

Elevated bile acids after Carprofen (Rimadyl) 400 reports · 0.8% of its reports
Elevated bile acids after Meloxicam (Metacam) 29 reports · 0.4% of its reports
Elevated bile acids after Firocoxib (Previcox) 26 reports · 0.3% of its reports

All reported side effects of Deracoxib in dogs · Medicines most reported with elevated bile acids