Vestibular disorder after Cyclosporine (Atopica) in dogs

The FDA has received 27 reports of vestibular disorder in dogs after Cyclosporine. That is 0.2% of all reports for this medicine, compared with 0.2% across reports for all dog medicines.

27Reports

59%Marked serious

7.4%Recovered

19%Died or euthanised

2 daysTypical onset

How soon it started

Same day

5 36%

1–2 days

3 21%

3–7 days

0 0.0%

1–4 weeks

3 21%

Over a month

3 21%

How the animals did

Recovered

2 7.4%

Still unwell when reported

6 22%

Died

1 3.7%

Euthanised

4 15%

Not known

14 52%

Problems reported at the same time

Nystagmus

14 52%

Head tilt - ear disorder

11 41%

9 33%

8 30%

8 30%

7 26%

Eye or vision problems

7 26%

Circling - neurological disorder

7 26%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Cyclosporine controls allergic skin disease and some immune conditions.

Products with this ingredient include Atopica. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Cyclosporine cause vestibular disorder in dogs?: 27 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vestibular disorder with similar medicines

Vestibular disorder after Oclacitinib (Apoquel) 50 reports · 0.2% of its reports

All reported side effects of Cyclosporine in dogs · Medicines most reported with vestibular disorder