Application site reaction after Chlorhexidine Gluconate + Ketoconazole + Phytosphingosine Salicyloyl in dogs

29 reports to the FDA describe application site reaction in dogs given Chlorhexidine Gluconate + Ketoconazole + Phytosphingosine Salicyloyl. That is 39% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

29Reports

3.4%Marked serious

62%Recovered

3.4%Died or euthanised

Same dayTypical onset

How soon it started

Same day

19 70%

1–2 days

5 19%

3–7 days

2 7.4%

1–4 weeks

1 3.7%

Over a month

0 0.0%

How the animals did

Recovered

17 59%

Recovered with lasting effects

1 3.4%

Still unwell when reported

7 24%

Died

1 3.4%

Not known

3 10%

Problems reported at the same time

Color, abnormal

3 10%

Skin redness

3 10%

Itching

1 3.4%

Death

1 3.4%

Skin slough

1 3.4%

Product problem

1 3.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Chlorhexidine Gluconate + Ketoconazole + Phytosphingosine Salicyloyl cause application site reaction in dogs?: 29 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Application site reaction with similar medicines

Application site reaction after Melarsomine (Immiticide) 22 reports · 0.1% of its reports
Application site reaction after Diphenhydramine 47 reports · 1.0% of its reports
Application site reaction after Butorphanol 28 reports · 0.6% of its reports
Application site reaction after Cefpodoxime 47 reports · 1.2% of its reports
Application site reaction after Tramadol 23 reports · 0.6% of its reports
Application site reaction after Florfenicol + Mometasone + Terbinafine 104 reports · 2.9% of its reports
Application site reaction after Isoflurane 20 reports · 0.7% of its reports
Application site reaction after Cephalexin 21 reports · 0.8% of its reports
Application site reaction after Famotidine 25 reports · 0.9% of its reports
Application site reaction after Clotrimazole + Gentamicin + Mometasone 42 reports · 1.6% of its reports

All reported side effects of Chlorhexidine Gluconate + Ketoconazole + Phytosphingosine Salicyloyl in dogs · Medicines most reported with application site reaction