Application site reaction after Florfenicol + Mometasone + Terbinafine in dogs

The FDA has received 104 reports of application site reaction in dogs after Florfenicol + Mometasone + Terbinafine. That is 2.9% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

104Reports
71%Marked serious
27%Recovered
2.9%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
28 32%
1–2 days
15 17%
3–7 days
16 18%
1–4 weeks
21 24%
Over a month
7 8.0%

How the animals did

Recovered
28 27%
Still unwell when reported
15 14%
Died
2 1.9%
Euthanised
1 1.0%
Not known
58 56%

Problems reported at the same time

Skin redness
34 33%
Didn't work as expected
27 26%
Head shake - ear disorder
20 19%
Swelling
18 17%
Itching
17 16%
Behaviour change
12 12%
Head tilt - ear disorder
12 12%
Loss of appetite
12 12%

Age of the animals

Under 1 year
8
1–3 years
36
4–7 years
26
8–11 years
14
12+ years
11

About this medicine

Type: medicine.

Questions owners ask

Can Florfenicol + Mometasone + Terbinafine cause application site reaction in dogs?
104 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Application site reaction with similar medicines

All reported side effects of Florfenicol + Mometasone + Terbinafine in dogs · Medicines most reported with application site reaction