Application site reaction after Cefpodoxime in dogs

47 reports to the FDA describe application site reaction in dogs given Cefpodoxime. That is 1.2% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

47Reports

53%Marked serious

40%Recovered

6.4%Died or euthanised

3 daysTypical onset

How soon it started

Same day

8 19%

1–2 days

12 28%

3–7 days

7 16%

1–4 weeks

13 30%

Over a month

3 7.0%

How the animals did

Recovered

19 40%

Still unwell when reported

7 15%

Died

1 2.1%

Euthanised

2 4.3%

Not known

18 38%

Problems reported at the same time

Itching

10 21%

Hair loss

10 21%

Injection site reaction

7 15%

Loss of appetite

5 11%

Didn't work as expected

5 11%

Death

4 8.5%

Swelling

4 8.5%

Skin redness

4 8.5%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause application site reaction in dogs?: 47 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Application site reaction with similar medicines

Application site reaction after Melarsomine (Immiticide) 22 reports · 0.1% of its reports
Application site reaction after Diphenhydramine 47 reports · 1.0% of its reports
Application site reaction after Butorphanol 28 reports · 0.6% of its reports
Application site reaction after Tramadol 23 reports · 0.6% of its reports
Application site reaction after Florfenicol + Mometasone + Terbinafine 104 reports · 2.9% of its reports
Application site reaction after Isoflurane 20 reports · 0.7% of its reports
Application site reaction after Cephalexin 21 reports · 0.8% of its reports
Application site reaction after Famotidine 25 reports · 0.9% of its reports
Application site reaction after Clotrimazole + Gentamicin + Mometasone 42 reports · 1.6% of its reports
Application site reaction after Betamethasone + Florfenicol + Terbinafine 79 reports · 3.2% of its reports

All reported side effects of Cefpodoxime in dogs · Medicines most reported with application site reaction