Didn't work as expected after Cephalexin in dogs

The FDA has received 316 reports of didn't work as expected in dogs after Cephalexin. That is 12% of all reports for this medicine, compared with 13% across reports for all dog medicines.

316Reports

31%Marked serious

5.1%Recovered

4.1%Died or euthanised

26 daysTypical onset

How soon it started

Same day

28 14%

1–2 days

15 7.5%

3–7 days

10 5.0%

1–4 weeks

59 30%

Over a month

87 44%

How the animals did

Recovered

12 3.8%

Recovered with lasting effects

4 1.3%

Still unwell when reported

193 61%

Died

8 2.5%

Euthanised

5 1.6%

Not known

94 30%

Problems reported at the same time

Lethargy

33 10%

Vomiting

33 10%

Loss of appetite

25 7.9%

Skin rash or irritation

25 7.9%

24 7.6%

20 6.3%

15 4.7%

15 4.7%

Age of the animals

Under 1 year

1–3 years

4–7 years

109

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Cephalexin cause didn't work as expected in dogs?: 316 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 26 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Melarsomine (Immiticide) 646 reports · 2.8% of its reports
Didn't work as expected after Polysulfated Glycosaminoglycan 698 reports · 13% of its reports
Didn't work as expected after Diphenhydramine 585 reports · 12% of its reports
Didn't work as expected after Butorphanol 1,022 reports · 23% of its reports
Didn't work as expected after Cefpodoxime 671 reports · 17% of its reports
Didn't work as expected after Tramadol 475 reports · 13% of its reports
Didn't work as expected after Florfenicol + Mometasone + Terbinafine 969 reports · 27% of its reports
Didn't work as expected after Desoxycorticosterone Pivalate 355 reports · 11% of its reports
Didn't work as expected after Propofol 600 reports · 20% of its reports
Didn't work as expected after Dirlotapide 712 reports · 25% of its reports

All reported side effects of Cephalexin in dogs · Medicines most reported with didn't work as expected