Behaviour change after Cephalexin in dogs

140 reports to the FDA describe behaviour change in dogs given Cephalexin. That is 5.2% of all reports for this medicine, compared with 2.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

140Reports
51%Marked serious
34%Recovered
12%Died or euthanised
7 daysTypical onset
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How soon it started

Same day
21 19%
1–2 days
17 15%
3–7 days
19 17%
1–4 weeks
29 26%
Over a month
26 23%

How the animals did

Recovered
39 28%
Recovered with lasting effects
9 6.4%
Still unwell when reported
41 29%
Died
6 4.3%
Euthanised
11 7.9%
Not known
34 24%

Problems reported at the same time

Age of the animals

Under 1 year
13
1–3 years
42
4–7 years
37
8–11 years
33
12+ years
14

About this medicine

Type: medicine.

Questions owners ask

Can Cephalexin cause behaviour change in dogs?
140 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 7 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Behaviour change with similar medicines

All reported side effects of Cephalexin in dogs · Medicines most reported with behaviour change