Musculoskeletal disorder after Cefpodoxime in dogs

31 reports to the FDA describe musculoskeletal disorder in dogs given Cefpodoxime. That is 0.8% of all reports for this medicine, compared with 0.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

31Reports

68%Marked serious

6.5%Recovered

23%Died or euthanised

5 daysTypical onset

How soon it started

Same day

4 20%

1–2 days

6 30%

3–7 days

1 5.0%

1–4 weeks

5 25%

Over a month

4 20%

How the animals did

Recovered

1 3.2%

Recovered with lasting effects

1 3.2%

Still unwell when reported

18 58%

Died

1 3.2%

Euthanised

6 19%

Not known

4 13%

Problems reported at the same time

12 39%

9 29%

9 29%

9 29%

7 23%

7 23%

6 19%

6 19%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause musculoskeletal disorder in dogs?: 31 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Musculoskeletal disorder with similar medicines

Musculoskeletal disorder after Melarsomine (Immiticide) 78 reports · 0.3% of its reports
Musculoskeletal disorder after Polysulfated Glycosaminoglycan 67 reports · 1.2% of its reports
Musculoskeletal disorder after Diphenhydramine 33 reports · 0.7% of its reports
Musculoskeletal disorder after Butorphanol 23 reports · 0.5% of its reports
Musculoskeletal disorder after Tramadol 87 reports · 2.3% of its reports
Musculoskeletal disorder after Desoxycorticosterone Pivalate 20 reports · 0.6% of its reports
Musculoskeletal disorder after Propofol 24 reports · 0.8% of its reports
Musculoskeletal disorder after Famotidine 49 reports · 1.9% of its reports
Musculoskeletal disorder after Chondroitin + Glucosamine 54 reports · 2.1% of its reports
Musculoskeletal disorder after Glucosamine 46 reports · 2.5% of its reports

All reported side effects of Cefpodoxime in dogs · Medicines most reported with musculoskeletal disorder