Eosinopenia after Cefpodoxime in dogs

The FDA has received 33 reports of eosinopenia in dogs after Cefpodoxime. That is 0.8% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

33Reports
64%Marked serious
12%Recovered
30%Died or euthanised
48 daysTypical onset
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How soon it started

Same day
1 4.2%
1–2 days
2 8.3%
3–7 days
0 0.0%
1–4 weeks
9 38%
Over a month
12 50%

How the animals did

Recovered
3 9.1%
Recovered with lasting effects
1 3.0%
Still unwell when reported
14 42%
Died
5 15%
Euthanised
5 15%
Not known
5 15%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
2
4–7 years
17
8–11 years
9
12+ years
0

About this medicine

Type: medicine.

Questions owners ask

Can Cefpodoxime cause eosinopenia in dogs?
33 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 48 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Eosinopenia with similar medicines

All reported side effects of Cefpodoxime in dogs · Medicines most reported with eosinopenia