Foaming at the mouth after Capromorelin (Entyce) in dogs

The FDA has received 32 reports of foaming at the mouth in dogs after Capromorelin. That is 2.1% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

32Reports

13%Marked serious

38%Recovered

6.3%Died or euthanised

Same dayTypical onset

How soon it started

Same day

25 81%

1–2 days

0 0.0%

3–7 days

4 13%

1–4 weeks

1 3.2%

Over a month

1 3.2%

How the animals did

Recovered

12 38%

Still unwell when reported

5 16%

Died

1 3.1%

Euthanised

1 3.1%

Not known

13 41%

Problems reported at the same time

8 25%

6 19%

6 19%

4 13%

Didn't work as expected

3 9.4%

Gagging

3 9.4%

Death

2 6.3%

Seizures

2 6.3%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Capromorelin stimulates appetite.

Products with this ingredient include Entyce, Elura. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Capromorelin cause foaming at the mouth in dogs?: 32 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Foaming at the mouth with similar medicines

Foaming at the mouth after Maropitant (Cerenia) 43 reports · 0.4% of its reports

All reported side effects of Capromorelin in dogs · Medicines most reported with foaming at the mouth