Hyperproteinaemia after Butorphanol in dogs

33 reports to the FDA describe hyperproteinaemia in dogs given Butorphanol. That is 0.7% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

33Reports

79%Marked serious

15%Recovered

48%Died or euthanised

4 daysTypical onset

How soon it started

Same day

2 7.4%

1–2 days

6 22%

3–7 days

10 37%

1–4 weeks

7 26%

Over a month

2 7.4%

How the animals did

Recovered

4 12%

Recovered with lasting effects

1 3.0%

Still unwell when reported

7 21%

Died

9 27%

Euthanised

7 21%

Not known

5 15%

Problems reported at the same time

24 73%

22 67%

20 61%

20 61%

15 45%

14 42%

14 42%

11 33%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Butorphanol cause hyperproteinaemia in dogs?: 33 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyperproteinaemia with similar medicines

Hyperproteinaemia after Melarsomine (Immiticide) 38 reports · 0.2% of its reports
Hyperproteinaemia after Tramadol 39 reports · 1.0% of its reports
Hyperproteinaemia after Famotidine 34 reports · 1.3% of its reports
Hyperproteinaemia after Ondansetron 20 reports · 3.0% of its reports

All reported side effects of Butorphanol in dogs · Medicines most reported with hyperproteinaemia