Intentional misuse after Buprenorphine in dogs

24 reports to the FDA describe intentional misuse in dogs given Buprenorphine. That is 1.5% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

24Reports

92%Marked serious

17%Recovered

13%Died or euthanised

Same dayTypical onset

How soon it started

Same day

12 52%

1–2 days

5 22%

3–7 days

1 4.3%

1–4 weeks

1 4.3%

Over a month

4 17%

How the animals did

Recovered

4 17%

Still unwell when reported

16 67%

Died

3 13%

Not known

1 4.2%

Problems reported at the same time

Didn't work as expected

7 29%

5 21%

5 21%

5 21%

5 21%

5 21%

4 17%

4 17%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause intentional misuse in dogs?: 24 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Intentional misuse with similar medicines

Intentional misuse after Dexmedetomidine (Dexdomitor) 80 reports · 1.5% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with intentional misuse