Dry mucous membrane after Buprenorphine in dogs

The FDA has received 43 reports of dry mucous membrane in dogs after Buprenorphine. That is 2.7% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

43Reports

86%Marked serious

21%Recovered

26%Died or euthanised

2 daysTypical onset

How soon it started

Same day

10 26%

1–2 days

13 34%

3–7 days

6 16%

1–4 weeks

2 5.3%

Over a month

7 18%

How the animals did

Recovered

9 21%

Still unwell when reported

15 35%

Died

4 9.3%

Euthanised

7 16%

Not known

8 19%

Problems reported at the same time

38 88%

30 70%

29 67%

22 51%

21 49%

18 42%

17 40%

15 35%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause dry mucous membrane in dogs?: 43 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Dry mucous membrane with similar medicines

Dry mucous membrane after Dexmedetomidine (Dexdomitor) 24 reports · 0.4% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with dry mucous membrane