Abnormal ultrasound finding after Buprenorphine in dogs

108 reports to the FDA describe abnormal ultrasound finding in dogs given Buprenorphine. That is 6.8% of all reports for this medicine, compared with 0.5% across reports for all dog medicines, so it is reported unusually often with this medicine.

108Reports

88%Marked serious

11%Recovered

47%Died or euthanised

4 daysTypical onset

How soon it started

Same day

24 26%

1–2 days

17 18%

3–7 days

14 15%

1–4 weeks

19 20%

Over a month

19 20%

How the animals did

Recovered

10 9.3%

Recovered with lasting effects

2 1.9%

Still unwell when reported

29 27%

Died

11 10%

Euthanised

40 37%

Not known

16 15%

Problems reported at the same time

76 70%

68 63%

67 62%

57 53%

51 47%

48 44%

43 40%

Abnormal radiograph finding

43 40%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Buprenorphine pain relief (an opioid).

Questions owners ask

Can Buprenorphine cause abnormal ultrasound finding in dogs?: 108 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 4 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Abnormal ultrasound finding with similar medicines

Abnormal ultrasound finding after Dexmedetomidine (Dexdomitor) 81 reports · 1.5% of its reports

All reported side effects of Buprenorphine in dogs · Medicines most reported with abnormal ultrasound finding