Spinosad (Comfortis) side effects in Bichon Frises

598 FDA reports involve Spinosad in a Bichon Frise. These are the problems they describe.

Vomiting
355 59%
Didn't stop fleas
129 22%
Lethargy
83 14%
Itching
47 7.9%
Loss of appetite
35 5.9%
Diarrhea
28 4.7%
Liver problems
19 3.2%
Unpalatable
18 3.0%
Tremors
16 2.7%
Behaviour change
16 2.7%
Seizures
15 2.5%
Didn't work as expected
14 2.3%

All reports for Spinosad in dogs