Hypochloraemia after Bordetella Vaccine in dogs

The FDA has received 61 reports of hypochloraemia in dogs after Bordetella Vaccine. That is 0.6% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

61Reports

90%Marked serious

11%Recovered

36%Died or euthanised

2 daysTypical onset

How soon it started

Same day

20 40%

1–2 days

6 12%

3–7 days

12 24%

1–4 weeks

6 12%

Over a month

6 12%

How the animals did

Recovered

6 9.8%

Recovered with lasting effects

1 1.6%

Still unwell when reported

23 38%

Died

6 9.8%

Euthanised

16 26%

Not known

9 15%

Problems reported at the same time

38 62%

37 61%

34 56%

32 52%

31 51%

29 48%

29 48%

23 38%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause hypochloraemia in dogs?: 61 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypochloraemia with similar medicines

Hypochloraemia after Rabies Vaccine 71 reports · 0.7% of its reports
Hypochloraemia after Leptospirosis Vaccine 48 reports · 0.6% of its reports
Hypochloraemia after Distemper-parvo Vaccine 38 reports · 0.6% of its reports

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with hypochloraemia