Hyponatremia after Bordetella Vaccine in dogs

50 reports to the FDA describe hyponatremia in dogs given Bordetella Vaccine. That is 0.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

50Reports

94%Marked serious

10%Recovered

50%Died or euthanised

1 daysTypical onset

How soon it started

Same day

17 39%

1–2 days

10 23%

3–7 days

8 18%

1–4 weeks

3 6.8%

Over a month

6 14%

How the animals did

Recovered

4 8.0%

Recovered with lasting effects

1 2.0%

Still unwell when reported

12 24%

Died

7 14%

Euthanised

18 36%

Not known

8 16%

Problems reported at the same time

37 74%

33 66%

31 62%

31 62%

30 60%

29 58%

26 52%

25 50%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Bordetella Vaccine cause hyponatremia in dogs?: 50 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hyponatremia with similar medicines

Hyponatremia after Rabies Vaccine 54 reports · 0.5% of its reports
Hyponatremia after Leptospirosis Vaccine 45 reports · 0.6% of its reports
Hyponatremia after Distemper-parvo Vaccine 39 reports · 0.6% of its reports

All reported side effects of Bordetella Vaccine in dogs · Medicines most reported with hyponatremia