Hypochloraemia after Rabies Vaccine in dogs

The FDA has received 71 reports of hypochloraemia in dogs after Rabies Vaccine. That is 0.7% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

71Reports

93%Marked serious

9.9%Recovered

35%Died or euthanised

3 daysTypical onset

How soon it started

Same day

19 31%

1–2 days

9 15%

3–7 days

12 20%

1–4 weeks

9 15%

Over a month

12 20%

How the animals did

Recovered

7 9.9%

Still unwell when reported

22 31%

Died

8 11%

Euthanised

17 24%

Not known

17 24%

Problems reported at the same time

47 66%

47 66%

40 56%

38 54%

38 54%

34 48%

31 44%

27 38%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause hypochloraemia in dogs?: 71 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 3 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hypochloraemia with similar medicines

Hypochloraemia after Bordetella Vaccine 61 reports · 0.6% of its reports
Hypochloraemia after Leptospirosis Vaccine 48 reports · 0.6% of its reports
Hypochloraemia after Distemper-parvo Vaccine 38 reports · 0.6% of its reports

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with hypochloraemia