Pale mucous membrane after Bedinvetmab (Librela) in dogs

The FDA has received 227 reports of pale mucous membrane in dogs after Bedinvetmab. That is 1.2% of all reports for this medicine, compared with 0.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

227Reports
96%Marked serious
13%Recovered
53%Died or euthanised
9 daysTypical onset
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How soon it started

Same day
60 30%
1–2 days
18 9.0%
3–7 days
21 10%
1–4 weeks
39 19%
Over a month
63 31%

How the animals did

Recovered
28 12%
Recovered with lasting effects
1 0.4%
Still unwell when reported
74 33%
Died
46 20%
Euthanised
74 33%
Not known
4 1.8%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
2
4–7 years
21
8–11 years
90
12+ years
112

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause pale mucous membrane in dogs?
227 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 9 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Pale mucous membrane with similar medicines

All reported side effects of Bedinvetmab in dogs · Medicines most reported with pale mucous membrane