Hind limb paralysis after Bedinvetmab (Librela) in dogs

The FDA has received 262 reports of hind limb paralysis in dogs after Bedinvetmab. That is 1.3% of all reports for this medicine, compared with 0.1% across reports for all dog medicines, so it is reported unusually often with this medicine.

262Reports

97%Marked serious

4.6%Recovered

49%Died or euthanised

7 daysTypical onset

How soon it started

Same day

57 25%

1–2 days

37 16%

3–7 days

33 14%

1–4 weeks

51 22%

Over a month

52 23%

How the animals did

Recovered

11 4.2%

Recovered with lasting effects

1 0.4%

Still unwell when reported

76 29%

Died

21 8.0%

Euthanised

108 41%

Not known

45 17%

Problems reported at the same time

129 49%

56 21%

50 19%

45 17%

40 15%

32 12%

29 11%

Proprioception deficit

23 8.8%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

100

12+ years

119

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause hind limb paralysis in dogs?: 262 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 7 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

All reported side effects of Bedinvetmab in dogs · Medicines most reported with hind limb paralysis