General illness after Bedinvetmab (Librela) in dogs

The FDA has received 300 reports of general illness in dogs after Bedinvetmab. That is 1.5% of all reports for this medicine, compared with 0.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

300Reports

65%Marked serious

2.7%Recovered

45%Died or euthanised

2 daysTypical onset

How soon it started

Same day

103 37%

1–2 days

41 15%

3–7 days

28 10%

1–4 weeks

53 19%

Over a month

52 19%

How the animals did

Recovered

8 2.7%

Still unwell when reported

68 23%

Died

58 19%

Euthanised

78 26%

Not known

88 29%

Problems reported at the same time

135 45%

57 19%

38 13%

31 10%

28 9.3%

26 8.7%

26 8.7%

24 8.0%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Bedinvetmab reduces osteoarthritis pain in dogs (monthly injection).

Products with this ingredient include Librela. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Bedinvetmab cause general illness in dogs?: 300 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

General illness with similar medicines

General illness after Lokivetmab (Cytopoint) 23 reports · 0.4% of its reports

All reported side effects of Bedinvetmab in dogs · Medicines most reported with general illness